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Life Extension Optimized Quercetin
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size:  1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin C (from ascorbic acid, camu-camu berry extract)
30 mg
33%
Quercetin (as quercetin dihydrate)
250 mg
**
Optimized Food Blend[onion (bulb) (extracts), bitter orange bioflavonoids (peel and fruit), apple (fruit)
220 mg
**
Camu-camu extract (wildcrafted berry)
50 mg
**

Top Medical Research Studies

8
Quercetin reduces cardiac fibrosis
Quercetin Alleviates Cardiac Fibrosis via Regulating the SIRT3 Signaling Pathway.
High relevance for cardiovascular health
We explored the effects of quercetin on cardiac fibrosis, a major concern in cardiovascular diseases. Using an experiment on mice, we administered quercetin after inducing cardiac stress and assessed its impact on heart function and fibrosis. Our findings showed that quercetin significantly reduced cardiac fibrosis and helped reverse cell proliferation caused by stress hormones. This protective effect was linked to its regulation of the SIRT3 signaling pathway. Overall, quercetin presents a promising avenue for addressing heart fibrosis.
Read More
8
Quercetin aids heart recovery post-infarction
Quercetin is a potential therapy for post-infarction NETosis formation.
Quercetin shows potential benefits
We examined the effects of quercetin on heart damage following a heart attack in rats. In our study, quercetin was administered just before reperfusion after a blockage in the heart's blood supply.

The results showed that quercetin significantly improved heart function and reduced harmful neutrophil formations. By lowering these formations, we believe quercetin may offer new hope as a protective treatment against heart injuries caused by reperfusion and inflammation.
Read More
9.5
Quercetin improves post-MI recovery
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
Relevance score: high
We investigated the potential of quercetin, a natural compound found in fruits and vegetables, to prevent challenges after a heart attack (myocardial infarction, or MI). By treating mice with quercetin before inducing MI, we observed significant improvements in heart function, survival rates, and reduced heart damage caused by inflammation and fibrosis.

The study also revealed that quercetin helps shift immune cells toward a healing state, crucial for recovery. This promising research opens the door for quercetin's use in treating cardiac issues related to heart attacks.
Read More

Most Useful Reviews

6.3
Promotes vascular integrity
This supplement helps maintain normal cholesterol levels, safeguarding the integrity of vascular endothelium and enhancing cardiovascular health. I've already completed one bottle and intend to continue taking it.
Read More
9.5
Alleviates Covid symptoms
Great quercetin! I chose it based on a recommendation from Dr Müller. It significantly aided my friends with Covid, allowing the disease to pass swiftly and without complications. Just one capsule a day is all you need. Highly recommend!
Read More
8.8
Combines immunity aids
This preparation, which combines quercetin with vitamin C and other beneficial extracts, excellently boosts immunity and accelerates recovery during illnesses. It helps maintain optimal cholesterol levels and positively affects the cardiovascular system.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.3
  • All Researches
9.5
Quercetin improves post-MI recovery
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
Relevance score: high
We investigated the potential of quercetin, a natural compound found in fruits and vegetables, to prevent challenges after a heart attack (myocardial infarction, or MI). By treating mice with quercetin before inducing MI, we observed significant improvements in heart function, survival rates, and reduced heart damage caused by inflammation and fibrosis.

The study also revealed that quercetin helps shift immune cells toward a healing state, crucial for recovery. This promising research opens the door for quercetin's use in treating cardiac issues related to heart attacks.
Read More
9
DBD enhances plaque stability
An integrative approach for mechanistic insights into the atherosclerotic plaque-stabilizing properties of Danggui Buxue decoction.
Highly relevant to cardiovascular research.
We examined the impact of Danggui Buxue Decoction (DBD), a traditional Chinese remedy, on atherosclerotic plaques in a mice model. Using a blend of advanced bioinformatics and experimental validation, we discovered that DBD can effectively stabilize these plaques.

Key ingredients like quercetin played a significant role in this process by targeting several important proteins that influence inflammation and lipid metabolism. Our findings suggest that quercetin and another compound, kaempferol, work together to improve heart health by reducing atherosclerotic vulnerability.
Read More
9
Quercetin may protect heart health
Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats.
Relevant study on heart treatments.
We examined how quercetin might protect against heart issues associated with menopause, particularly by looking at its effects on cardiac reperfusion arrhythmias in ovariectomized rats. Over a four-week period, we found that quercetin significantly reduced heart damage and improved mitochondrial function by enhancing ATP production. This suggests quercetin may help manage some heart health risks tied to decreased estrogen levels. While our findings are promising, further research in humans is needed to confirm these effects.
Read More
9
Quercetin protects platelet function
Quercetin inhibits platelet activation and ER-stress mediated autophagy in response to extracellular histone.
Highly relevant to cardiovascular health
We investigated the effects of quercetin (QUE), a natural dietary phytochemical, on platelet toxicity induced by extracellular histones, which can harm our body during critical illnesses.

In our study, we set up experiments to observe how histones trigger platelet activation and the protective influence of QUE. Our findings revealed that QUE successfully reduced platelet activation and protected against stress-induced damage.

This suggests that quercetin could be a promising candidate for addressing platelet-related issues associated with histones.
Read More
9
Quercetin provides protective effects
Dynamic and quantitative assessment of quercetin for cardiac oxidative stress injury prevention using sensitive cardiomyocyte based biosensing.
Important for cardiovascular research.
We developed an innovative biosensing platform to explore how quercetin affects heart cells, especially during cardiac oxidative stress. By testing cardiomyocytes, we found that quercetin can protect against injury caused by oxidative stress, highlighting its potential as a therapeutic option.

However, we also determined a safe concentration limit and noted potential long-term effects on heart cells. This balanced evaluation not only sheds light on quercetin's advantages but also emphasizes the need for careful consideration in its use for cardiovascular health.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
6.3
Promotes vascular integrity
This supplement helps maintain normal cholesterol levels, safeguarding the integrity of vascular endothelium and enhancing cardiovascular health. I've already completed one bottle and intend to continue taking it.
9.5
Alleviates Covid symptoms
Great quercetin! I chose it based on a recommendation from Dr Müller. It significantly aided my friends with Covid, allowing the disease to pass swiftly and without complications. Just one capsule a day is all you need. Highly recommend!
8.8
Combines immunity aids
This preparation, which combines quercetin with vitamin C and other beneficial extracts, excellently boosts immunity and accelerates recovery during illnesses. It helps maintain optimal cholesterol levels and positively affects the cardiovascular system.
8
Enhances immunity
I heard that quercetin can combat epidemics and boost immunity. Even if you contract the illness, it can help lessen the effects. While many brands are out of stock, I tried this one. The capsules are slightly large but manageable.
8.8
Stimulates immune response
Quercetin promotes healthy cellular function and cardiovascular health and has been shown to enhance a healthy immune response, particularly during seasonal changes.
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